Vms1p is a release factor for the ribosome-associated quality control complex
The ribosome-associated quality control complex (RQC) functions to disassemble stalled ribosomes. Here the authors find that the tRNA hydrolase Vms1 is involved in the release of nascent peptide from stalled ribosomes.
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Nature Publishing Group
2018-06-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-018-04564-3 |
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doaj-3a55ccb06f334a70b5dd8fbbc32464c7 |
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Article |
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doaj-3a55ccb06f334a70b5dd8fbbc32464c72021-05-11T09:33:28ZengNature Publishing GroupNature Communications2041-17232018-06-01911910.1038/s41467-018-04564-3Vms1p is a release factor for the ribosome-associated quality control complexOlga Zurita Rendón0Eric K. Fredrickson1Conor J. Howard2Jonathan Van Vranken3Sarah Fogarty4Neal D. Tolley5Raghav Kalia6Beatriz A. Osuna7Peter S. Shen8Christopher P. Hill9Adam Frost10Jared Rutter11Howard Hughes Medical InstituteDepartment of Biochemistry, University of Utah School of MedicineDepartment of Biochemistry and Biophysics, University of California, San FranciscoDepartment of Biochemistry, University of Utah School of MedicineHoward Hughes Medical InstituteMolecular Medicine Program, University of UtahDepartment of Biochemistry, University of Utah School of MedicineDepartment of Biochemistry and Biophysics, University of California, San FranciscoDepartment of Biochemistry, University of Utah School of MedicineDepartment of Biochemistry, University of Utah School of MedicineDepartment of Biochemistry, University of Utah School of MedicineHoward Hughes Medical InstituteThe ribosome-associated quality control complex (RQC) functions to disassemble stalled ribosomes. Here the authors find that the tRNA hydrolase Vms1 is involved in the release of nascent peptide from stalled ribosomes.https://doi.org/10.1038/s41467-018-04564-3 |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Olga Zurita Rendón Eric K. Fredrickson Conor J. Howard Jonathan Van Vranken Sarah Fogarty Neal D. Tolley Raghav Kalia Beatriz A. Osuna Peter S. Shen Christopher P. Hill Adam Frost Jared Rutter |
| spellingShingle |
Olga Zurita Rendón Eric K. Fredrickson Conor J. Howard Jonathan Van Vranken Sarah Fogarty Neal D. Tolley Raghav Kalia Beatriz A. Osuna Peter S. Shen Christopher P. Hill Adam Frost Jared Rutter Vms1p is a release factor for the ribosome-associated quality control complex Nature Communications |
| author_facet |
Olga Zurita Rendón Eric K. Fredrickson Conor J. Howard Jonathan Van Vranken Sarah Fogarty Neal D. Tolley Raghav Kalia Beatriz A. Osuna Peter S. Shen Christopher P. Hill Adam Frost Jared Rutter |
| author_sort |
Olga Zurita Rendón |
| title |
Vms1p is a release factor for the ribosome-associated quality control complex |
| title_short |
Vms1p is a release factor for the ribosome-associated quality control complex |
| title_full |
Vms1p is a release factor for the ribosome-associated quality control complex |
| title_fullStr |
Vms1p is a release factor for the ribosome-associated quality control complex |
| title_full_unstemmed |
Vms1p is a release factor for the ribosome-associated quality control complex |
| title_sort |
vms1p is a release factor for the ribosome-associated quality control complex |
| publisher |
Nature Publishing Group |
| series |
Nature Communications |
| issn |
2041-1723 |
| publishDate |
2018-06-01 |
| description |
The ribosome-associated quality control complex (RQC) functions to disassemble stalled ribosomes. Here the authors find that the tRNA hydrolase Vms1 is involved in the release of nascent peptide from stalled ribosomes. |
| url |
https://doi.org/10.1038/s41467-018-04564-3 |
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