Data set of the toxic effects of divaricatic acid depside on Biomphalaria glabrata and Schistosoma mansoni cercariae

Data set of the toxic effects of divaricatic acid depside on Biomphalaria glabrata and Schistosoma mansoni cercariae

In this study, the molluscicidal and antiparasitic activities of divaricatic acid was evaluated, targeting the mollusc Biomphalaria glabrata and cercariae of the helminth Schistosoma mansoni. Divaricatic acid showed high toxicity against both adult snails (5.5 μg/mL) and embryos (20 μg/mL after 6 h...

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Main Authors: H.A.M.F. Silva, W.N. Siqueira, J.L.F. Sá, L.R.S. Silva, M.C.B. Martins, A.L. Aires, F.F. Amâncio, E.C. Pereira, M.C.P.A. Albuquerque, A.M.M.A. Melo, N.H. Silva
Format: Article
Language:English
Published: Elsevier 2018-08-01
Series:Data in Brief
Online Access:http://www.sciencedirect.com/science/article/pii/S2352340918305778
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spelling doaj-3a5214bdfce74b9e874e35e608599c1e2020-11-25T02:12:46ZengElsevierData in Brief2352-34092018-08-011913931397Data set of the toxic effects of divaricatic acid depside on Biomphalaria glabrata and Schistosoma mansoni cercariaeH.A.M.F. Silva0W.N. Siqueira1J.L.F. Sá2L.R.S. Silva3M.C.B. Martins4A.L. Aires5F.F. Amâncio6E.C. Pereira7M.C.P.A. Albuquerque8A.M.M.A. Melo9N.H. Silva10Laboratório de Produtos Naturais, Departamento de Bioquímica, Universidade Federal de Pernambuco, Recife, PE, BrazilDepartamento de Energia Nuclear, Universidade Federal de Pernambuco, Recife, PE, Brazil; Laboratório de Radiobiologia, Departamento de Biofísica e Radiobiologia, Universidade Federal de Pernambuco, Recife, PE, Brazil; Corresponding author at: Departamento de Energia Nuclear, Universidade Federal de Pernambuco, Recife PE, BrazilLaboratório de Produtos Naturais, Departamento de Bioquímica, Universidade Federal de Pernambuco, Recife, PE, BrazilLaboratório de Radiobiologia, Departamento de Biofísica e Radiobiologia, Universidade Federal de Pernambuco, Recife, PE, BrazilLaboratório de Produtos Naturais, Departamento de Bioquímica, Universidade Federal de Pernambuco, Recife, PE, BrazilLaboratório de Imunopatologia Keizo Asami (LIKA), Universidade Federal de Pernambuco, Recife, PE, BrazilLaboratório de Radiobiologia, Departamento de Biofísica e Radiobiologia, Universidade Federal de Pernambuco, Recife, PE, BrazilLaboratório de Geografia Ambiental, Departamento de Ciências Geográficas, Universidade Federal de Pernambuco, PE, BrazilLaboratório de Imunopatologia Keizo Asami (LIKA), Universidade Federal de Pernambuco, Recife, PE, BrazilLaboratório de Radiobiologia, Departamento de Biofísica e Radiobiologia, Universidade Federal de Pernambuco, Recife, PE, BrazilLaboratório de Produtos Naturais, Departamento de Bioquímica, Universidade Federal de Pernambuco, Recife, PE, BrazilIn this study, the molluscicidal and antiparasitic activities of divaricatic acid was evaluated, targeting the mollusc Biomphalaria glabrata and cercariae of the helminth Schistosoma mansoni. Divaricatic acid showed high toxicity against both adult snails (5.5 μg/mL) and embryos (20 μg/mL after 6 h of exposure). Similar activity was observed in S. mansoni cercariae after only a short exposure time. The divaricatic acid proved to be a promising substance for the control of the snail B. glabrata, an intermediate host of schistosomiasis, as well as the cercariae of the pathogen. Keywords: Lichen substances, Schistosoma mansoni, Biomphalaria glabrata, Molluscicide activityhttp://www.sciencedirect.com/science/article/pii/S2352340918305778
collection DOAJ
language English
format Article
sources DOAJ
author H.A.M.F. Silva
W.N. Siqueira
J.L.F. Sá
L.R.S. Silva
M.C.B. Martins
A.L. Aires
F.F. Amâncio
E.C. Pereira
M.C.P.A. Albuquerque
A.M.M.A. Melo
N.H. Silva
spellingShingle H.A.M.F. Silva
W.N. Siqueira
J.L.F. Sá
L.R.S. Silva
M.C.B. Martins
A.L. Aires
F.F. Amâncio
E.C. Pereira
M.C.P.A. Albuquerque
A.M.M.A. Melo
N.H. Silva
Data set of the toxic effects of divaricatic acid depside on Biomphalaria glabrata and Schistosoma mansoni cercariae
Data in Brief
author_facet H.A.M.F. Silva
W.N. Siqueira
J.L.F. Sá
L.R.S. Silva
M.C.B. Martins
A.L. Aires
F.F. Amâncio
E.C. Pereira
M.C.P.A. Albuquerque
A.M.M.A. Melo
N.H. Silva
author_sort H.A.M.F. Silva
title Data set of the toxic effects of divaricatic acid depside on Biomphalaria glabrata and Schistosoma mansoni cercariae
title_short Data set of the toxic effects of divaricatic acid depside on Biomphalaria glabrata and Schistosoma mansoni cercariae
title_full Data set of the toxic effects of divaricatic acid depside on Biomphalaria glabrata and Schistosoma mansoni cercariae
title_fullStr Data set of the toxic effects of divaricatic acid depside on Biomphalaria glabrata and Schistosoma mansoni cercariae
title_full_unstemmed Data set of the toxic effects of divaricatic acid depside on Biomphalaria glabrata and Schistosoma mansoni cercariae
title_sort data set of the toxic effects of divaricatic acid depside on biomphalaria glabrata and schistosoma mansoni cercariae
publisher Elsevier
series Data in Brief
issn 2352-3409
publishDate 2018-08-01
description In this study, the molluscicidal and antiparasitic activities of divaricatic acid was evaluated, targeting the mollusc Biomphalaria glabrata and cercariae of the helminth Schistosoma mansoni. Divaricatic acid showed high toxicity against both adult snails (5.5 μg/mL) and embryos (20 μg/mL after 6 h of exposure). Similar activity was observed in S. mansoni cercariae after only a short exposure time. The divaricatic acid proved to be a promising substance for the control of the snail B. glabrata, an intermediate host of schistosomiasis, as well as the cercariae of the pathogen. Keywords: Lichen substances, Schistosoma mansoni, Biomphalaria glabrata, Molluscicide activity
url http://www.sciencedirect.com/science/article/pii/S2352340918305778
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