FasR Regulates Fatty Acid Biosynthesis and Is Essential for Virulence of Mycobacterium tuberculosis

Mycobacterium tuberculosis, the etiologic agent of human tuberculosis, is the world’s leading cause of death from an infectious disease. One of the main features of this pathogen is the complex and dynamic lipid composition of the cell envelope, which adapts to the variable host environment and defi...

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Bibliographic Details
Main Authors: Sonia Mondino, Cristina L. Vázquez, Matías Cabruja, Claudia Sala, Amaury Cazenave-Gassiot, Federico C. Blanco, Markus R. Wenk, Fabiana Bigi, Stewart T. Cole, Hugo Gramajo, Gabriela Gago
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Microbiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2020.586285/full