Liposomal gp100 vaccine combined with CpG ODN sensitizes established B16F10 melanoma tumors to anti PD-1 therapy

Liposomal gp100 vaccine combined with CpG ODN sensitizes established B16F10 melanoma tumors to anti PD-1 therapy

<em><strong>Objective(s):</strong></em> Program death 1 (PD-1)/ program death-ligand 1 (PD-L1) pathways, as the main inhibitory checkpoints, induce immunosuppression in the tumor microenvironment (TME). Despite the importance of inhibitor checkpoint receptor (ICR) blockers, t...

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Bibliographic Details
Main Authors: Mona Yazdani, Mahdi Hatamipour, Behrang Alani, Hossein Nikzad, Naama Mohammadian Roshan, Javad Verdi, Mahmoud Reza Jaafari, Mahdi Noureddini, Ali Badiee
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2020-08-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
anti pd
1 monoclonal
antibody cpg odn gp100 liposome melanoma
Online Access:http://ijbms.mums.ac.ir/article_15684_4b6307458d67fce6bd3c845465e5dac8.pdf

Internet

http://ijbms.mums.ac.ir/article_15684_4b6307458d67fce6bd3c845465e5dac8.pdf

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