Occupational noise exposure and Raynaud’s phenomenon: a nested case–control study

The primary aim of this study was to determine if self-reported occupational noise exposure was associated with Raynaud’s phenomenon. In northern Sweden, a nested case–control study was performed on subjects reporting Raynaud’s phenomenon (N=461), and controls (N=763) matched by age, sex and geograp...

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Main Authors: Albin Stjernbrandt, Mahmoud Abu Mdaighem, Hans Pettersson
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:International Journal of Circumpolar Health
Subjects:
Online Access:http://dx.doi.org/10.1080/22423982.2021.1969745
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spelling doaj-3a25a49ebcc04309b0c60a25d424d6a22021-08-24T15:34:22ZengTaylor & Francis GroupInternational Journal of Circumpolar Health2242-39822021-01-0180110.1080/22423982.2021.19697451969745Occupational noise exposure and Raynaud’s phenomenon: a nested case–control studyAlbin Stjernbrandt0Mahmoud Abu Mdaighem1Hans Pettersson2Umeå UniversityUmeå UniversityUmeå UniversityThe primary aim of this study was to determine if self-reported occupational noise exposure was associated with Raynaud’s phenomenon. In northern Sweden, a nested case–control study was performed on subjects reporting Raynaud’s phenomenon (N=461), and controls (N=763) matched by age, sex and geographical location. The response rate to the exposure questionnaire was 79.2%. The study showed no statistically significant association between occupational noise exposure and reporting Raynaud’s phenomenon (OR 1.10; 95% CI 0.83–1.46) in simple analyses. However, there was a trend towards increasing OR for Raynaud’s phenomenon with increasing noise exposure, although not statistically significant. Also, there was a significant association between noise exposure and hearing loss (OR 2.76; 95% CI 2.00–3.81), and hearing loss was associated with reporting Raynaud’s phenomenon (OR 1.52; 95% CI 1.03–2.23) in a multiple regression model. In conclusion, self-reported occupational noise exposure was not statistically significantly associated with Raynaud’s phenomenon, but there was a dose–effect trend. In addition, the multiple model showed a robust association between hearing loss and Raynaud’s phenomenon. These findings offer some support for a common pathophysiological background for Raynaud’s phenomenon and hearing loss among noise-exposed workers, possibly through noise-induced vasoconstriction.http://dx.doi.org/10.1080/22423982.2021.1969745(mesh): raynaud diseasenoiseoccupationalhearing losshand-arm vibration syndromehereditysweden
collection DOAJ
language English
format Article
sources DOAJ
author Albin Stjernbrandt
Mahmoud Abu Mdaighem
Hans Pettersson
spellingShingle Albin Stjernbrandt
Mahmoud Abu Mdaighem
Hans Pettersson
Occupational noise exposure and Raynaud’s phenomenon: a nested case–control study
International Journal of Circumpolar Health
(mesh): raynaud disease
noise
occupational
hearing loss
hand-arm vibration syndrome
heredity
sweden
author_facet Albin Stjernbrandt
Mahmoud Abu Mdaighem
Hans Pettersson
author_sort Albin Stjernbrandt
title Occupational noise exposure and Raynaud’s phenomenon: a nested case–control study
title_short Occupational noise exposure and Raynaud’s phenomenon: a nested case–control study
title_full Occupational noise exposure and Raynaud’s phenomenon: a nested case–control study
title_fullStr Occupational noise exposure and Raynaud’s phenomenon: a nested case–control study
title_full_unstemmed Occupational noise exposure and Raynaud’s phenomenon: a nested case–control study
title_sort occupational noise exposure and raynaud’s phenomenon: a nested case–control study
publisher Taylor & Francis Group
series International Journal of Circumpolar Health
issn 2242-3982
publishDate 2021-01-01
description The primary aim of this study was to determine if self-reported occupational noise exposure was associated with Raynaud’s phenomenon. In northern Sweden, a nested case–control study was performed on subjects reporting Raynaud’s phenomenon (N=461), and controls (N=763) matched by age, sex and geographical location. The response rate to the exposure questionnaire was 79.2%. The study showed no statistically significant association between occupational noise exposure and reporting Raynaud’s phenomenon (OR 1.10; 95% CI 0.83–1.46) in simple analyses. However, there was a trend towards increasing OR for Raynaud’s phenomenon with increasing noise exposure, although not statistically significant. Also, there was a significant association between noise exposure and hearing loss (OR 2.76; 95% CI 2.00–3.81), and hearing loss was associated with reporting Raynaud’s phenomenon (OR 1.52; 95% CI 1.03–2.23) in a multiple regression model. In conclusion, self-reported occupational noise exposure was not statistically significantly associated with Raynaud’s phenomenon, but there was a dose–effect trend. In addition, the multiple model showed a robust association between hearing loss and Raynaud’s phenomenon. These findings offer some support for a common pathophysiological background for Raynaud’s phenomenon and hearing loss among noise-exposed workers, possibly through noise-induced vasoconstriction.
topic (mesh): raynaud disease
noise
occupational
hearing loss
hand-arm vibration syndrome
heredity
sweden
url http://dx.doi.org/10.1080/22423982.2021.1969745
work_keys_str_mv AT albinstjernbrandt occupationalnoiseexposureandraynaudsphenomenonanestedcasecontrolstudy
AT mahmoudabumdaighem occupationalnoiseexposureandraynaudsphenomenonanestedcasecontrolstudy
AT hanspettersson occupationalnoiseexposureandraynaudsphenomenonanestedcasecontrolstudy
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