Occupational noise exposure and Raynaud’s phenomenon: a nested case–control study
The primary aim of this study was to determine if self-reported occupational noise exposure was associated with Raynaud’s phenomenon. In northern Sweden, a nested case–control study was performed on subjects reporting Raynaud’s phenomenon (N=461), and controls (N=763) matched by age, sex and geograp...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2021-01-01
|
Series: | International Journal of Circumpolar Health |
Subjects: | |
Online Access: | http://dx.doi.org/10.1080/22423982.2021.1969745 |
id |
doaj-3a25a49ebcc04309b0c60a25d424d6a2 |
---|---|
record_format |
Article |
spelling |
doaj-3a25a49ebcc04309b0c60a25d424d6a22021-08-24T15:34:22ZengTaylor & Francis GroupInternational Journal of Circumpolar Health2242-39822021-01-0180110.1080/22423982.2021.19697451969745Occupational noise exposure and Raynaud’s phenomenon: a nested case–control studyAlbin Stjernbrandt0Mahmoud Abu Mdaighem1Hans Pettersson2Umeå UniversityUmeå UniversityUmeå UniversityThe primary aim of this study was to determine if self-reported occupational noise exposure was associated with Raynaud’s phenomenon. In northern Sweden, a nested case–control study was performed on subjects reporting Raynaud’s phenomenon (N=461), and controls (N=763) matched by age, sex and geographical location. The response rate to the exposure questionnaire was 79.2%. The study showed no statistically significant association between occupational noise exposure and reporting Raynaud’s phenomenon (OR 1.10; 95% CI 0.83–1.46) in simple analyses. However, there was a trend towards increasing OR for Raynaud’s phenomenon with increasing noise exposure, although not statistically significant. Also, there was a significant association between noise exposure and hearing loss (OR 2.76; 95% CI 2.00–3.81), and hearing loss was associated with reporting Raynaud’s phenomenon (OR 1.52; 95% CI 1.03–2.23) in a multiple regression model. In conclusion, self-reported occupational noise exposure was not statistically significantly associated with Raynaud’s phenomenon, but there was a dose–effect trend. In addition, the multiple model showed a robust association between hearing loss and Raynaud’s phenomenon. These findings offer some support for a common pathophysiological background for Raynaud’s phenomenon and hearing loss among noise-exposed workers, possibly through noise-induced vasoconstriction.http://dx.doi.org/10.1080/22423982.2021.1969745(mesh): raynaud diseasenoiseoccupationalhearing losshand-arm vibration syndromehereditysweden |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Albin Stjernbrandt Mahmoud Abu Mdaighem Hans Pettersson |
spellingShingle |
Albin Stjernbrandt Mahmoud Abu Mdaighem Hans Pettersson Occupational noise exposure and Raynaud’s phenomenon: a nested case–control study International Journal of Circumpolar Health (mesh): raynaud disease noise occupational hearing loss hand-arm vibration syndrome heredity sweden |
author_facet |
Albin Stjernbrandt Mahmoud Abu Mdaighem Hans Pettersson |
author_sort |
Albin Stjernbrandt |
title |
Occupational noise exposure and Raynaud’s phenomenon: a nested case–control study |
title_short |
Occupational noise exposure and Raynaud’s phenomenon: a nested case–control study |
title_full |
Occupational noise exposure and Raynaud’s phenomenon: a nested case–control study |
title_fullStr |
Occupational noise exposure and Raynaud’s phenomenon: a nested case–control study |
title_full_unstemmed |
Occupational noise exposure and Raynaud’s phenomenon: a nested case–control study |
title_sort |
occupational noise exposure and raynaud’s phenomenon: a nested case–control study |
publisher |
Taylor & Francis Group |
series |
International Journal of Circumpolar Health |
issn |
2242-3982 |
publishDate |
2021-01-01 |
description |
The primary aim of this study was to determine if self-reported occupational noise exposure was associated with Raynaud’s phenomenon. In northern Sweden, a nested case–control study was performed on subjects reporting Raynaud’s phenomenon (N=461), and controls (N=763) matched by age, sex and geographical location. The response rate to the exposure questionnaire was 79.2%. The study showed no statistically significant association between occupational noise exposure and reporting Raynaud’s phenomenon (OR 1.10; 95% CI 0.83–1.46) in simple analyses. However, there was a trend towards increasing OR for Raynaud’s phenomenon with increasing noise exposure, although not statistically significant. Also, there was a significant association between noise exposure and hearing loss (OR 2.76; 95% CI 2.00–3.81), and hearing loss was associated with reporting Raynaud’s phenomenon (OR 1.52; 95% CI 1.03–2.23) in a multiple regression model. In conclusion, self-reported occupational noise exposure was not statistically significantly associated with Raynaud’s phenomenon, but there was a dose–effect trend. In addition, the multiple model showed a robust association between hearing loss and Raynaud’s phenomenon. These findings offer some support for a common pathophysiological background for Raynaud’s phenomenon and hearing loss among noise-exposed workers, possibly through noise-induced vasoconstriction. |
topic |
(mesh): raynaud disease noise occupational hearing loss hand-arm vibration syndrome heredity sweden |
url |
http://dx.doi.org/10.1080/22423982.2021.1969745 |
work_keys_str_mv |
AT albinstjernbrandt occupationalnoiseexposureandraynaudsphenomenonanestedcasecontrolstudy AT mahmoudabumdaighem occupationalnoiseexposureandraynaudsphenomenonanestedcasecontrolstudy AT hanspettersson occupationalnoiseexposureandraynaudsphenomenonanestedcasecontrolstudy |
_version_ |
1721197240549113856 |