Sulphatation does not appear to be a protective mechanism to prevent oxysterol accumulation in humans and mice.

Sulphatation does not appear to be a protective mechanism to prevent oxysterol accumulation in humans and mice.

24S- and 27-hydroxycholesterol (24OHC and 27OHC) are potent regulators of different biochemical systems in vitro and are the major circulating oxysterols. A small fraction of these oxysterols has been reported to be sulphated but there are no detailed studies. We considered the possibility that sulp...

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Main Authors: Jure Acimovic, Anita Lövgren-Sandblom, Maria Olin, Zeina Ali, Maura Heverin, Rebecca Schüle, Ludger Schöls, Björn Fischler, Peter Fickert, Michael Trauner, Ingemar Björkhem
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3700920?pdf=render

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