Serological survey of hantavirus in rodents in Uberlândia, Minas Gerais, Brazil Inquérito sorológico de hantavírus em roedores, Uberlândia, Minas Gerais, Brasil

We conducted a serological survey to determine the presence of hantavirus infection in rodents in Uberlândia, Minas Gerais as well as to identify and characterize associated factors. Rodents were captured using Sherman live-capture traps set in rural and peri-urban environments. A total of...

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Main Authors: Jean Ezequiel Limongi, Fernando Guimarães Moreira, Joel Batista Peres, Akemi Suzuki, Ivani Bisordi Ferreira, Renato Pereira Souza, Rogério Melo Costa Pinto, Luiz Eloy Pereira
Format: Article
Language:English
Published: Universidade de São Paulo 2013-06-01
Series:Revista do Instituto de Medicina Tropical de São Paulo
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652013000300155
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spelling doaj-3a1c2a9180cd4957b7d3fde5c415fbd62020-11-25T00:27:58ZengUniversidade de São PauloRevista do Instituto de Medicina Tropical de São Paulo0036-46651678-99462013-06-01553155158Serological survey of hantavirus in rodents in Uberlândia, Minas Gerais, Brazil Inquérito sorológico de hantavírus em roedores, Uberlândia, Minas Gerais, BrasilJean Ezequiel LimongiFernando Guimarães MoreiraJoel Batista PeresAkemi SuzukiIvani Bisordi FerreiraRenato Pereira SouzaRogério Melo Costa PintoLuiz Eloy PereiraWe conducted a serological survey to determine the presence of hantavirus infection in rodents in Uberl&#226;ndia, Minas Gerais as well as to identify and characterize associated factors. Rodents were captured using Sherman live-capture traps set in rural and peri-urban environments. A total of 611 rodents were captured. There was a higher trap success in peri-urban areas (26.3%) and a higher prevalence of antibodies among rodents captured in rural areas (2.9%). Necromys lasiurus was the most common species (42.2%) and the more frequently infected (4.6%). One Calomys tener (1/141; 0.7%) and one Calomys sp. (1/14; 7.1%) were also positive for the hantavirus infection. In N. lasiurus, antibody prevalence correlated with population density (p < 0.01), age class (p = 0.003) and presence of scars (p = 0.02). The data confirm that horizontal transmission is the main mechanism that maintains the virus in nature. The higher seropositivity in N. lasiurus is consistent with genetic studies that associate this species with an Araraquara virus reservoir; the seropositivity of C. tener and Calomys sp. may indicate the occurrence of spillover infection or the presence of other circulating hantaviruses.<br>Realizamos um estudo transversal para identificar a presen&#231;a de infec&#231;&#227;o por hantav&#237;rus em roedores em Uberl&#226;ndia, Minas Gerais, e tamb&#233;m para identificar e caracterizar fatores associados. Roedores foram capturados usando armadilhas do tipo Sherman em ambientes rural e periurbano. Um total de 611 roedores foi capturado. Houve maior sucesso de captura na &#225;rea periurbana (26,3%) e maior preval&#234;ncia de anticorpos entre os roedores capturados na &#225;rea rural (2,9%). Necromys lasiurus foi a esp&#233;cie mais encontrada (42,2%) e a mais frequentemente infectada (4,6%). Um Calomys tener (1/141; 0.7%) e um Calomys sp. (1/14; 7.1%) foram tamb&#233;m positivos. Os dados obtidos mostram que em N. lasiurus, a preval&#234;ncia de anticorpos est&#225; relacionada &#224; densidade populacional (p < 0.01), a classe de idade (p = 0.003) e a presen&#231;a de cicatrizes (p = 0.02), confirmando que a transmiss&#227;o horizontal &#233; o principal mecanismo que mant&#233;m o v&#237;rus na natureza. A maior positividade em N. lasiurus &#233; consistente com estudos gen&#233;ticos que permitem associar esta esp&#233;cie como reservat&#243;rio do v&#237;rus Araraquara; a soropositividade de C. tener e Calomys sp. pode indicar a ocorr&#234;ncia de "spillover infection" ou a presen&#231;a de outros hantav&#237;rus circulantes.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652013000300155HantavirusRodentiaBrazil
collection DOAJ
language English
format Article
sources DOAJ
author Jean Ezequiel Limongi
Fernando Guimarães Moreira
Joel Batista Peres
Akemi Suzuki
Ivani Bisordi Ferreira
Renato Pereira Souza
Rogério Melo Costa Pinto
Luiz Eloy Pereira
spellingShingle Jean Ezequiel Limongi
Fernando Guimarães Moreira
Joel Batista Peres
Akemi Suzuki
Ivani Bisordi Ferreira
Renato Pereira Souza
Rogério Melo Costa Pinto
Luiz Eloy Pereira
Serological survey of hantavirus in rodents in Uberlândia, Minas Gerais, Brazil Inquérito sorológico de hantavírus em roedores, Uberlândia, Minas Gerais, Brasil
Revista do Instituto de Medicina Tropical de São Paulo
Hantavirus
Rodentia
Brazil
author_facet Jean Ezequiel Limongi
Fernando Guimarães Moreira
Joel Batista Peres
Akemi Suzuki
Ivani Bisordi Ferreira
Renato Pereira Souza
Rogério Melo Costa Pinto
Luiz Eloy Pereira
author_sort Jean Ezequiel Limongi
title Serological survey of hantavirus in rodents in Uberlândia, Minas Gerais, Brazil Inquérito sorológico de hantavírus em roedores, Uberlândia, Minas Gerais, Brasil
title_short Serological survey of hantavirus in rodents in Uberlândia, Minas Gerais, Brazil Inquérito sorológico de hantavírus em roedores, Uberlândia, Minas Gerais, Brasil
title_full Serological survey of hantavirus in rodents in Uberlândia, Minas Gerais, Brazil Inquérito sorológico de hantavírus em roedores, Uberlândia, Minas Gerais, Brasil
title_fullStr Serological survey of hantavirus in rodents in Uberlândia, Minas Gerais, Brazil Inquérito sorológico de hantavírus em roedores, Uberlândia, Minas Gerais, Brasil
title_full_unstemmed Serological survey of hantavirus in rodents in Uberlândia, Minas Gerais, Brazil Inquérito sorológico de hantavírus em roedores, Uberlândia, Minas Gerais, Brasil
title_sort serological survey of hantavirus in rodents in uberlândia, minas gerais, brazil inquérito sorológico de hantavírus em roedores, uberlândia, minas gerais, brasil
publisher Universidade de São Paulo
series Revista do Instituto de Medicina Tropical de São Paulo
issn 0036-4665
1678-9946
publishDate 2013-06-01
description We conducted a serological survey to determine the presence of hantavirus infection in rodents in Uberl&#226;ndia, Minas Gerais as well as to identify and characterize associated factors. Rodents were captured using Sherman live-capture traps set in rural and peri-urban environments. A total of 611 rodents were captured. There was a higher trap success in peri-urban areas (26.3%) and a higher prevalence of antibodies among rodents captured in rural areas (2.9%). Necromys lasiurus was the most common species (42.2%) and the more frequently infected (4.6%). One Calomys tener (1/141; 0.7%) and one Calomys sp. (1/14; 7.1%) were also positive for the hantavirus infection. In N. lasiurus, antibody prevalence correlated with population density (p < 0.01), age class (p = 0.003) and presence of scars (p = 0.02). The data confirm that horizontal transmission is the main mechanism that maintains the virus in nature. The higher seropositivity in N. lasiurus is consistent with genetic studies that associate this species with an Araraquara virus reservoir; the seropositivity of C. tener and Calomys sp. may indicate the occurrence of spillover infection or the presence of other circulating hantaviruses.<br>Realizamos um estudo transversal para identificar a presen&#231;a de infec&#231;&#227;o por hantav&#237;rus em roedores em Uberl&#226;ndia, Minas Gerais, e tamb&#233;m para identificar e caracterizar fatores associados. Roedores foram capturados usando armadilhas do tipo Sherman em ambientes rural e periurbano. Um total de 611 roedores foi capturado. Houve maior sucesso de captura na &#225;rea periurbana (26,3%) e maior preval&#234;ncia de anticorpos entre os roedores capturados na &#225;rea rural (2,9%). Necromys lasiurus foi a esp&#233;cie mais encontrada (42,2%) e a mais frequentemente infectada (4,6%). Um Calomys tener (1/141; 0.7%) e um Calomys sp. (1/14; 7.1%) foram tamb&#233;m positivos. Os dados obtidos mostram que em N. lasiurus, a preval&#234;ncia de anticorpos est&#225; relacionada &#224; densidade populacional (p < 0.01), a classe de idade (p = 0.003) e a presen&#231;a de cicatrizes (p = 0.02), confirmando que a transmiss&#227;o horizontal &#233; o principal mecanismo que mant&#233;m o v&#237;rus na natureza. A maior positividade em N. lasiurus &#233; consistente com estudos gen&#233;ticos que permitem associar esta esp&#233;cie como reservat&#243;rio do v&#237;rus Araraquara; a soropositividade de C. tener e Calomys sp. pode indicar a ocorr&#234;ncia de "spillover infection" ou a presen&#231;a de outros hantav&#237;rus circulantes.
topic Hantavirus
Rodentia
Brazil
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652013000300155
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