Zika virus infection induces endoplasmic reticulum stress and apoptosis in placental trophoblasts

Zika virus infection induces endoplasmic reticulum stress and apoptosis in placental trophoblasts

Abstract Zika virus (ZIKV) infection to a pregnant woman can be vertically transmitted to the fetus via the placenta leading to Congenital Zika syndrome. This is characterized by microcephaly, retinal defects, and intrauterine growth retardation. ZIKV induces placental trophoblast apoptosis leading...

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Bibliographic Details
Main Authors: Philma Glora Muthuraj, Prakash K. Sahoo, Madison Kraus, Taylor Bruett, Arun S. Annamalai, Aryamav Pattnaik, Asit K. Pattnaik, Siddappa N. Byrareddy, Sathish Kumar Natarajan
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-020-00379-8

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