Comparison of the composition of lymphocyte subpopulations in non-relapse and relapse patients with squamous cell carcinoma of the head and neck before, during radiochemotherapy and in the follow-up period: a multicenter prospective study of the German Cancer Consortium Radiation Oncology Group (DKTK-ROG)

Comparison of the composition of lymphocyte subpopulations in non-relapse and relapse patients with squamous cell carcinoma of the head and neck before, during radiochemotherapy and in the follow-up period: a multicenter prospective study of the German Cancer Consortium Radiation Oncology Group (DKTK-ROG)

Abstract Background Radiochemotherapy (RCT) has been shown to induce changes in immune cell homeostasis which might affect antitumor immune responses. In the present study, we aimed to compare the composition and kinetics of major lymphocyte subsets in the periphery of patients with non-locoregional...

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Main Authors: Minli Niu, Stephanie E. Combs, Annett Linge, Mechthild Krause, Michael Baumann, Fabian Lohaus, Nadja Ebert, Ingeborg Tinhofer, Volker Budach, Jens von der Grün, Franz Rödel, Anca-Ligia Grosu, Gabriele Multhoff
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Radiation Oncology
Subjects:
SCCHN
Prediction of locoregional recurrence
Immunophenotyping
Radiochemotherapy
Lymphocyte subpopulations
NK cell subsets
Online Access:https://doi.org/10.1186/s13014-021-01868-5

Internet

https://doi.org/10.1186/s13014-021-01868-5

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