Age and Chronicity of Administration Dramatically Influenced the Impact of Low Dose Paraquat Exposure on Behavior and Hypothalamic-Pituitary-Adrenal Activity

Age and Chronicity of Administration Dramatically Influenced the Impact of Low Dose Paraquat Exposure on Behavior and Hypothalamic-Pituitary-Adrenal Activity

Little is known of the age-dependent and long-term consequences of low exposure levels of the herbicide and dopaminergic toxicant, paraquat. Thus, we assessed the dose-dependent effects of paraquat using a typical short-term (3 week) exposure procedure, followed by an assessment of the effects of ch...

Full description

Bibliographic Details
Main Authors: Chris A. Rudyk, Jessica McNeill, Natalie Prowse, Zach Dwyer, Kyle Farmer, Darcy Litteljohn, Warren Caldwell, Shawn Hayley
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-07-01
Series:Frontiers in Aging Neuroscience
Subjects:
paraquat
oxidative stress
aging
Parkinson’s disease
behavior
Online Access:http://journal.frontiersin.org/article/10.3389/fnagi.2017.00222/full

Internet

http://journal.frontiersin.org/article/10.3389/fnagi.2017.00222/full

Similar Items