Overstimulation of NMDA receptors impairs early brain development in vivo.

Overstimulation of NMDA receptors impairs early brain development in vivo.

BACKGROUND: Brains of patients with schizophrenia show both neurodevelopmental and functional deficits that suggest aberrant glutamate neurotransmission. Evidence from both genetic and pharmacological studies suggests that glutamatergic dysfunction, particularly with involvement of NMDARs, plays a c...

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Bibliographic Details
Main Authors: Tomomi Aida, Yoshimasa Ito, Yuko K Takahashi, Kohichi Tanaka
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3350466?pdf=render

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