Suppressive Effects of the Site 1 Protease (S1P) Inhibitor, PF-429242, on Dengue Virus Propagation

Suppressive Effects of the Site 1 Protease (S1P) Inhibitor, PF-429242, on Dengue Virus Propagation

Dengue virus (DENV) infection causes one of the most widespread mosquito-borne diseases in the world. Despite the great need, effective vaccines and practical antiviral therapies are still under development. Intracellular lipid levels are regulated by sterol regulatory elements-binding proteins (SRE...

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Bibliographic Details
Main Authors: Leo Uchida, Shuzo Urata, Gianne Eduard L. Ulanday, Yuki Takamatsu, Jiro Yasuda, Kouichi Morita, Daisuke Hayasaka
Format: Article
Language:English
Published: MDPI AG 2016-02-01
Series:Viruses
Subjects:
dengue virus
antivirus drug
PF-429242
SREBPs
S1P
Online Access:http://www.mdpi.com/1999-4915/8/2/46

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