Anti-Inflammatory Action and Mechanisms of Resveratrol

Resveratrol (3,4′,5-trihy- droxystilbene), a natural phytoalexin polyphenol, exhibits anti-oxidant, anti-inflammatory, and anti-carcinogenic properties. This phytoalexin is well-absorbed and rapidly and extensively metabolized in the body. Inflammation is an adaptive response, which could be trigger...

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Main Authors: Tiantian Meng, Dingfu Xiao, Arowolo Muhammed, Juying Deng, Liang Chen, Jianhua He
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/26/1/229
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spelling doaj-3a02ce11578243c799e7e3a645bbaa7d2021-01-06T00:00:27ZengMDPI AGMolecules1420-30492021-01-012622922910.3390/molecules26010229Anti-Inflammatory Action and Mechanisms of ResveratrolTiantian Meng0Dingfu Xiao1Arowolo Muhammed2Juying Deng3Liang Chen4Jianhua He5College of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, ChinaCollege of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, ChinaCollege of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, ChinaCollege of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, ChinaHuaihua Institute of Agricultural Sciences, No.140 Yingfeng East Road, Hecheng District, Huaihua 418000, ChinaCollege of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, ChinaResveratrol (3,4′,5-trihy- droxystilbene), a natural phytoalexin polyphenol, exhibits anti-oxidant, anti-inflammatory, and anti-carcinogenic properties. This phytoalexin is well-absorbed and rapidly and extensively metabolized in the body. Inflammation is an adaptive response, which could be triggered by various danger signals, such as invasion by microorganisms or tissue injury. In this review, the anti-inflammatory activity and the mechanism of resveratrol modulates the inflammatory response are examined. Multiple experimental studies that illustrate regulatory mechanisms and the immunomodulatory function of resveratrol both in vivo and in vitro. The data acquired from those studies are discussed.https://www.mdpi.com/1420-3049/26/1/229resveratrolabsorption and metabolismanti-inflammationantioxidantmechanism
collection DOAJ
language English
format Article
sources DOAJ
author Tiantian Meng
Dingfu Xiao
Arowolo Muhammed
Juying Deng
Liang Chen
Jianhua He
spellingShingle Tiantian Meng
Dingfu Xiao
Arowolo Muhammed
Juying Deng
Liang Chen
Jianhua He
Anti-Inflammatory Action and Mechanisms of Resveratrol
Molecules
resveratrol
absorption and metabolism
anti-inflammation
antioxidant
mechanism
author_facet Tiantian Meng
Dingfu Xiao
Arowolo Muhammed
Juying Deng
Liang Chen
Jianhua He
author_sort Tiantian Meng
title Anti-Inflammatory Action and Mechanisms of Resveratrol
title_short Anti-Inflammatory Action and Mechanisms of Resveratrol
title_full Anti-Inflammatory Action and Mechanisms of Resveratrol
title_fullStr Anti-Inflammatory Action and Mechanisms of Resveratrol
title_full_unstemmed Anti-Inflammatory Action and Mechanisms of Resveratrol
title_sort anti-inflammatory action and mechanisms of resveratrol
publisher MDPI AG
series Molecules
issn 1420-3049
publishDate 2021-01-01
description Resveratrol (3,4′,5-trihy- droxystilbene), a natural phytoalexin polyphenol, exhibits anti-oxidant, anti-inflammatory, and anti-carcinogenic properties. This phytoalexin is well-absorbed and rapidly and extensively metabolized in the body. Inflammation is an adaptive response, which could be triggered by various danger signals, such as invasion by microorganisms or tissue injury. In this review, the anti-inflammatory activity and the mechanism of resveratrol modulates the inflammatory response are examined. Multiple experimental studies that illustrate regulatory mechanisms and the immunomodulatory function of resveratrol both in vivo and in vitro. The data acquired from those studies are discussed.
topic resveratrol
absorption and metabolism
anti-inflammation
antioxidant
mechanism
url https://www.mdpi.com/1420-3049/26/1/229
work_keys_str_mv AT tiantianmeng antiinflammatoryactionandmechanismsofresveratrol
AT dingfuxiao antiinflammatoryactionandmechanismsofresveratrol
AT arowolomuhammed antiinflammatoryactionandmechanismsofresveratrol
AT juyingdeng antiinflammatoryactionandmechanismsofresveratrol
AT liangchen antiinflammatoryactionandmechanismsofresveratrol
AT jianhuahe antiinflammatoryactionandmechanismsofresveratrol
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