Into the intracellular logistics of cross-presentation

The induction of cytotoxic CD8+ T cell responses requires the presentation of antigenic peptides by MHC class I molecules (MHC I). MHC I usually present peptides derived from endogenous proteins. However, some subtypes of dendritic cells (DCs) have developed the ability to efficiently present peptid...

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Bibliographic Details
Main Authors: Charlotte eSadaka, Jacques eNeefjes
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-02-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00031/full