MCF-7 and its Multidrug Resistant Variant MCF-7/ADR Overcome TNF Cytotoxicity through Prevention of Reactive Oxygen Species Accumulation

MCF-7 and its Multidrug Resistant Variant MCF-7/ADR Overcome TNF Cytotoxicity through Prevention of Reactive Oxygen Species Accumulation

Background: Signal transduction of numerous cytokines and growth factors are mediated by reactive oxygen species (ROS). Tumor necrosis factor-α (TNF-α) have stimulated accumulation of ROS in various in vitro studies. MCF-7 and its Adriamycin resistant variant MCF-7/ADR are resistant against TNF-α cy...

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Bibliographic Details
Main Authors: Morteza Ghandadi, Javad Behravan, Samira Biabani, Sara Abbaspor, Fatemeh Mosaffa
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2019-06-01
Series:Pharmaceutical Sciences
Subjects:
Breast cancer
MCF-7
Multidrug resistance;
ROS
TNF-α
Online Access:https://ps.tbzmed.ac.ir/PDF/Pharm-31751

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