mTORC1 signalling mediates PI3K-dependent large lipid droplet accumulation in Drosophila ovarian nurse cells

mTORC1 signalling mediates PI3K-dependent large lipid droplet accumulation in Drosophila ovarian nurse cells

Insulin and insulin-like growth factor signalling (IIS), which is primarily mediated by the PI3-kinase (PI3K)/PTEN/Akt kinase signalling cassette, is a highly evolutionarily conserved pathway involved in co-ordinating growth, development, ageing and nutrient homeostasis with dietary intake. It contr...

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Bibliographic Details
Main Authors:	Lawrence B. Mensah, Deborah C. I. Goberdhan, Clive Wilson
Format:	Article
Language:	English
Published:	The Company of Biologists 2017-05-01
Series:	Biology Open
Subjects:	Obesity Triacylglycerol Tsc1 Tsc2 Akt Insulin
Online Access:	http://bio.biologists.org/content/6/5/563

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