Anandamide, Acting via CB2 Receptors, Alleviates LPS-Induced Neuroinflammation in Rat Primary Microglial Cultures

Anandamide, Acting via CB2 Receptors, Alleviates LPS-Induced Neuroinflammation in Rat Primary Microglial Cultures

Microglial activation is a polarized process divided into potentially neuroprotective phenotype M2 and neurotoxic phenotype M1, predominant during chronic neuroinflammation. Endocannabinoid system provides an attractive target to control the balance between microglial phenotypes. Anandamide as an im...

Full description

Bibliographic Details
Main Authors:	Natalia Malek, Katarzyna Popiolek-Barczyk, Joanna Mika, Barbara Przewlocka, Katarzyna Starowicz
Format:	Article
Language:	English
Published:	Hindawi Limited 2015-01-01
Series:	Neural Plasticity
Online Access:	http://dx.doi.org/10.1155/2015/130639

Similar Items

Delta-opioid receptor analgesia is independent of microglial activation in a rat model of neuropathic pain.
by: Joanna Mika, et al.
Published: (2014-01-01)

Biphalin, a Dimeric Enkephalin, Alleviates LPS-Induced Activation in Rat Primary Microglial Cultures in Opioid Receptor-Dependent and Receptor-Independent Manners
by: Katarzyna Popiolek-Barczyk, et al.
Published: (2017-01-01)

Alterations in the Anandamide Metabolism in the Development of Neuropathic Pain
by: Natalia Malek, et al.
Published: (2014-01-01)

Effects of LPLI on microglial phagocytosis in LPS-induced neuroinflammation model
by: Sheng Song, et al.
Published: (2014-05-01)

Comparison of the Expression Changes after Botulinum Toxin Type A and Minocycline Administration in Lipopolysaccharide-Stimulated Rat Microglial and Astroglial Cultures
by: Joanna Mika, et al.
Published: (2017-04-01)

The Endocannabinoid, Anandamide, Acts as a Novel Inhibitor of LPS-Induced Inflammasome Activation in Human Gastric Cancer AGS Cell Line: Involvement of CB1 and TRPV1 Receptors
by: Sahar Sadat Sedeighzadeh, et al.
Published: (2021-01-01)

Role of FKBP51 in the modulation of LPS-induced microglial activation and neuroinflammation
by: Wan-Jung Lin, et al.
Published: (2019)

Molecular Understanding of the Activation of CB1 and Blockade of TRPV1 Receptors: Implications for Novel Treatment Strategies in Osteoarthritis
by: Jakub Mlost, et al.
Published: (2018-01-01)

Idebenone Alleviates Neuroinflammation and Modulates Microglial Polarization in LPS-Stimulated BV2 Cells and MPTP-Induced Parkinson’s Disease Mice
by: Aijuan Yan, et al.
Published: (2019-01-01)

Full inhibition of spinal FAAH leads to TRPV1-mediated analgesic effects in neuropathic rats and possible lipoxygenase-mediated remodeling of anandamide metabolism.
by: Katarzyna Starowicz, et al.
Published: (2013-01-01)

Dual mechanism of TRKB activation by anandamide through CB1 and TRPV1 receptors
by: Cassiano R.A.F. Diniz, et al.
Published: (2019-02-01)

Dual-acting compounds targeting endocannabinoid and endovanilloid systems — a novel treatment option for chronic pain management.
by: Natalia Malek, et al.
Published: (2016-08-01)

Anandamide capacitates bull spermatozoa through CB1 and TRPV1 activation.
by: María Gracia Gervasi, et al.
Published: (2011-02-01)

Alterations in Anandamide Synthesis and Degradation during Osteoarthritis Progression in an Animal Model
by: Marta Bryk, et al.
Published: (2020-10-01)

PD98059 Influences Immune Factors and Enhances Opioid Analgesia in Model of Neuropathy.
by: Ewelina Rojewska, et al.
Published: (2015-01-01)

Anandamide suppresses proliferation and cytokine release from primary human T-lymphocytes mainly via CB2 receptors.
by: Maria Teresa Cencioni, et al.
Published: (2010-01-01)

Stabilization of Brain Mast Cells Alleviates LPS-Induced Neuroinflammation by Inhibiting Microglia Activation
by: Hongquan Dong, et al.
Published: (2019-05-01)

LPS-induced proNGF synthesis and release in the N9 and BV2 microglial cells: a new pathway underling microglial toxicity in neuroinflammation.
by: Li Duan, et al.
Published: (2013-01-01)

Blockade of Cannabinoid CB1 Receptors in the Dorsal Periaqueductal Gray Unmasks the Antinociceptive Effect of Local Injections of Anandamide in Mice
by: Diego C. Mascarenhas, et al.
Published: (2017-10-01)

Botulinum Toxin Type A—A Modulator of Spinal Neuron–Glia Interactions under Neuropathic Pain Conditions
by: Ewelina Rojewska, et al.
Published: (2018-04-01)

Insights from molecular docking and molecular dynamics on the potential of vitexin as an antagonist candidate against lipopolysaccharide (LPS) for microglial activation in neuroinflammation
by: M. A. F. Yahaya, et al.
Published: (2021-06-01)

Microglial exosomes in retinal neuroinflammation: focus in glaucoma
by: Inês Dinis Aires, et al.
Published: (2021-01-01)

Microglial metabolic disturbances and neuroinflammation in cerebral infarction
by: Haruna Takeda, et al.
Published: (2021-01-01)

Anandamide Protects HT22 Cells Exposed to Hydrogen Peroxide by Inhibiting CB1 Receptor-Mediated Type 2 NADPH Oxidase
by: Ji Jia, et al.
Published: (2014-01-01)

Neuroprotection by dihydrotestosterone in LPS-induced neuroinflammation
by: Lei Yang, et al.
Published: (2020-07-01)

Role of FAAH-like anandamide transporter in anandamide inactivation.
by: Kwannok Leung, et al.
Published: (2013-01-01)

Mer regulates microglial/macrophage M1/M2 polarization and alleviates neuroinflammation following traumatic brain injury
by: Haijian Wu, et al.
Published: (2021-01-01)

Minocycline Enhances the Effectiveness of Nociceptin/Orphanin FQ during Neuropathic Pain
by: Katarzyna Popiolek-Barczyk, et al.
Published: (2014-01-01)

Terpenoids from <i>Abies holophylla</i> Attenuate LPS-Induced Neuroinflammation in Microglial Cells by Suppressing the JNK-Related Signaling Pathway
by: Lalita Subedi, et al.
Published: (2021-01-01)

Stimulation of cannabinoid receptor 2 (CB<sub>2</sub>) suppresses microglial activation
by: Fernandez Francisco, et al.
Published: (2005-12-01)

Control of Neuroinflammation through Radiation-Induced Microglial Changes
by: Alexandra Boyd, et al.
Published: (2021-09-01)

The novel role of extracellular cardiolipin in microglial activation and neuroinflammation
by: Pointer, Caitlin Bennett
Published: (2017)

Phosphoinositides: Roles in the Development of Microglial-Mediated Neuroinflammation and Neurodegeneration
by: Thomas Ernest James Phillips, et al.
Published: (2021-03-01)

Inhibition of Neuroinflammation in LPS-Activated Microglia by Cryptolepine
by: Olumayokun A. Olajide, et al.
Published: (2013-01-01)

Characterization of biotin-anandamide, a novel tool for the visualization of anandamide accumulation
by: Filomena Fezza, et al.
Published: (2008-06-01)

Sphingosine kinase 1 deficiency exacerbates LPS-induced neuroinflammation.
by: Natalia M Grin'kina, et al.
Published: (2012-01-01)

Inhibitory Effects of Betulinic Acid on LPS-Induced Neuroinflammation Involve M2 Microglial Polarization via CaMKKβ-Dependent AMPK Activation
by: Chuwen Li, et al.
Published: (2018-04-01)

Sexually divergent induction of microglial-associated neuroinflammation with hippocampal aging
by: Colleen A. Mangold, et al.
Published: (2017-07-01)

Seleno-polymannuronate attenuates neuroinflammation by suppressing microglial and astrocytic activation
by: Decheng Bi, et al.
Published: (2018-12-01)

Involvement of the Microglial Aryl Hydrocarbon Receptor in Neuroinflammation and Vasogenic Edema after Ischemic Stroke
by: Miki Tanaka, et al.
Published: (2021-03-01)