The Effect of Low-Dose Proteasome Inhibition on Pre-Existing Atherosclerosis in LDL Receptor-Deficient Mice

The Effect of Low-Dose Proteasome Inhibition on Pre-Existing Atherosclerosis in LDL Receptor-Deficient Mice

Dysfunction of the ubiquitin-proteasome system (UPS) has been implicated in atherosclerosis development. However, the nature of UPS dysfunction has been proposed to be specific to certain stages of atherosclerosis development, which has implications for proteasome inhibition as a potential treatment...

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Bibliographic Details
Main Authors: Nicola Wilck, Mandy Fechner, Cristian Dan, Verena Stangl, Karl Stangl, Antje Ludwig
Format: Article
Language:English
Published: MDPI AG 2017-04-01
Series:International Journal of Molecular Sciences
Subjects:
atherosclerosis
proteasome inhibition
inflammation
Online Access:http://www.mdpi.com/1422-0067/18/4/781

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