CB1 receptor antagonist rimonabant protects against chronic intermittent hypoxia-induced renal injury in rats
Abstract Background Obstructive sleep apnoea (OSA) induced chronic kidney disease is mainly caused by chronic intermittent hypoxia (CIH). Our study investigate the mechanism underlying CIH-induced renal damage and whether the cannabinoid receptor 1 (CB1R) antagonist rimonabant (Ri) alleviates CIH-in...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-04-01
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Series: | BMC Nephrology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12882-021-02362-6 |