In vitro activity of phospholipase A 2 and of peptides from Crotalus durissus terrificus venom against amastigote and promastigote forms of Leishmania (L.) infantum chagasi

In vitro activity of phospholipase A 2 and of peptides from Crotalus durissus terrificus venom against amastigote and promastigote forms of Leishmania (L.) infantum chagasi

Abstract Background American visceral leishmaniasis is caused by the intracellular parasiteLeishmania (L.) infantum chagasi, and transmitted by the sand fly Lutzomyia longipalpis. Since treatment is based on classical chemotherapeutics with significant side effects, the search for new drugs remain...

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Bibliographic Details
Main Authors: Gustavo A. C. Barros, Andreia V. Pereira, Luciana C. Barros, Airton Lourenço Jr, Sueli A. Calvi, Lucilene D. Santos, Benedito Barraviera, Rui Seabra Ferreira Jr
Format: Article
Language:English
Published: SciELO 2015-12-01
Series:Journal of Venomous Animals and Toxins including Tropical Diseases
Subjects:
PLA2
Peptides
Crotalus dutissus terrificus
Venom
Leishmanicidal activity
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992015000100351&lng=en&tlng=en

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