Epithelial plasticity can generate multi-lineage phenotypes in human and murine bladder cancers
Recent studies have utilized bulk tumour mRNA sequencing to classify bladder cancers into distinct subgroups. Here, the authors use single cell transcriptomic analysis and cell transplant studies to show that epithelial plasticity can generate basal, luminal and mesenchymal phenotypes in human and m...
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Bibliographic Details
| Main Authors: |
John P. Sfakianos,
Jorge Daza,
Yang Hu,
Harry Anastos,
Geoffrey Bryant,
Rohan Bareja,
Ketan K. Badani,
Matthew D. Galsky,
Olivier Elemento,
Bishoy M. Faltas,
David J. Mulholland |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Publishing Group
2020-05-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-020-16162-3
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