Comparative genomic analyses of a virulent pseudorabies virus and a series of its in vitro passaged strains

Comparative genomic analyses of a virulent pseudorabies virus and a series of its in vitro passaged strains

Abstract Background Pseudorabies virus (PRV) of the family Herpesviridae is the causative agent of Aujeszky’s disease. Attenuation of PRV by serial passaging in vitro is a well-established method; however, the dynamic variations occurring on viral genome during this process have not been characteriz...

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Bibliographic Details
Main Authors: Chao Ye, Jiqiang Wu, Wu Tong, Tongling Shan, Xuefei Cheng, Jingjing Xu, Chao Liang, Hao Zheng, Guoxin Li, Guangzhi Tong
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Virology Journal
Subjects:
Pseudorabies virus
Genomic analyses
Passaging
Attenuation
Dynamic variation
Online Access:http://link.springer.com/article/10.1186/s12985-018-1102-8

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http://link.springer.com/article/10.1186/s12985-018-1102-8

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