Chronic myelogenous leukemia on target

Abstract Chronic myelogenous leukemia (CML) is commonly treated with tyrosine kinase inhibitors (TKIs) that inhibit the pro‐leukemic activity of the BCR‐ABL1 oncoprotein. Despite the therapeutic progress mediated by TKI use, off‐target effects, treatment‐induced drug resistance, and the limited effe...

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Bibliographic Details
Main Authors: Veronika Némethová, Filip Rázga
Format: Article
Language:English
Published: Wiley 2018-07-01
Series:Cancer Medicine
Subjects:
Online Access:https://doi.org/10.1002/cam4.1604