Analysis of Transcriptome, Selected Intracellular Signaling Pathways, Proliferation and Apoptosis of LNCaP Cells Exposed to High Leptin Concentrations

Analysis of Transcriptome, Selected Intracellular Signaling Pathways, Proliferation and Apoptosis of LNCaP Cells Exposed to High Leptin Concentrations

Leptin, the first discovered adipokine, has been connected to various physiological and pathophysiological processes, including cancerogenesis. Increasing evidence confirms its influence on prostate cancer cells. However, studies on the effects of leptin on the proliferation and apoptosis of the and...

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Bibliographic Details
Main Authors: Marta Szyszka, Lukasz Paschke, Marianna Tyczewska, Karol Jopek, Piotr Celichowski, Paulina Milecka, Gulnara Sultanova, Ewelina Stelcer, Agnieszka Malinska, Ludwik K. Malendowicz, Marcin Rucinski
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:International Journal of Molecular Sciences
Subjects:
prostate cancer cells
lncap
leptin
transcriptome analysis
proliferation
apoptosis
intracellular signaling pathways
Online Access:https://www.mdpi.com/1422-0067/20/21/5412

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