CD68, CD163, and matrix metalloproteinase 9 (MMP-9) co-localization in breast tumor microenvironment predicts survival differently in ER-positive and -negative cancers

CD68, CD163, and matrix metalloproteinase 9 (MMP-9) co-localization in breast tumor microenvironment predicts survival differently in ER-positive and -negative cancers

Abstract Background The role of tumor-associated macrophages (TAMs) in the cancer immune landscape and their potential as treatment targets or modulators of response to treatment are gaining increasing interest. TAMs display high molecular and functional complexity. Therefore their objective assessm...

Full description

Bibliographic Details
Main Authors: Vasiliki Pelekanou, Franz Villarroel-Espindola, Kurt A. Schalper, Lajos Pusztai, David L. Rimm
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Breast Cancer Research
Subjects:
Tumor-associated macrophages
Matrix metalloproteinase-9
Breast cancer
Online Access:http://link.springer.com/article/10.1186/s13058-018-1076-x

Similar Items

Similar Items