Hepatitis C Virus-Induced Monocyte Differentiation Into Polarized M2 Macrophages Promotes Stellate Cell Activation via TGF-βSummary
Background & Aims: Monocyte and macrophage (MΦ) activation contributes to the pathogenesis of chronic hepatitis C virus (HCV) infection. Disease pathogenesis is regulated by both liver-resident MΦs and monocytes recruited as precursors of MΦs into the damaged liver. Monocytes differentiate in...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2016-05-01
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Series: | Cellular and Molecular Gastroenterology and Hepatology |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2352345X16000023 |