Protective effects of a novel drug RC28-E blocking both VEGF and FGF2 on early diabetic rat retina

Protective effects of a novel drug RC28-E blocking both VEGF and FGF2 on early diabetic rat retina

AIM: To investigate protective effects of a novel recombinant decoy receptor drug RC28-E on retinal damage in early diabetic rats. METHODS: The streptozotocin (STZ)-induced diabetic rats were randomly divided into 6 groups: diabetes mellitus (DM) group (saline, 3 μL/eye); RC28-E at low (0.33 μg/μL,...

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Bibliographic Details
Main Authors: Qian-Hui Yang, Yan Zhang, Jing Jiang, Mian-Mian Wu, Qian Han, Qi-Yu Bo, Guang-Wei Yu, Yu-Sha Ru, Xun Liu, Min Huang, Ling Wang, Xiao-Min Zhang, Jian-Min Fang, Xiao-Rong Li
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2018-06-01
Series:International Journal of Ophthalmology
Subjects:
944
diabetic retinopathy
vascular endothelial growth factor
fibroblast growth factor 2
recombinant decoy receptor
retinal damage
diabetes
Online Access:http://www.ijo.cn/en_publish/2018/6/20180607.pdf

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