Effect and neurohumoral changes of laparoscopic and ureteroscopic surgery for treatment of complicated upper ureteral calculi

• Main Authors: Cheng-Jun Qiu, Jin-Song Ao, Li Cheng, Bo Wang
• Format: Article
• Language: English
• Published: Editorial Board of Journal of Hainan Medical University 2016-12-01
• Series: Journal of Hainan Medical University
• Subjects: Complicated upper ureteral calculi; Laparoscope; Ureteroscopic surgery; Neurohumor
• Online Access: http://www.hnykdxxb.com/PDF/201623/18.pdf
• ISSN: 1007-1237; 1007-1237

Objective: To analyze the effect and neurohumoral changes of laparoscopic and ureteroscopic surgery for treatment of complicated upper ureteral calculi. Methods: A total of 92 patients with complicated upper ureteral calculi who received surgical treatment in our hospital between March 2014 and March 2016 were selected and randomly divided into observation group and control group, control group received ureteroscopic surgery and observation group received laparoscopic ureterolithotomy. Surgical success rate and calculus removal success rate of two groups of patients were observed; 6 h after operation, neurohumoral indexes were detected. Results: Surgical success rate and calculus removal rate of observation group were higher than those of control group; 6 h after operation, renal function indexes CysC, Urea and Cr content in serum of observation group were lower than those of control group, inflammatory factors IL-1 β, IL-6, IL-8, PCT, TNF-α and hs-CRP content in serum were lower than those of control group, stress hormones Cor, ALD, NE, Ang-Ⅱ and ACTH content in serum were lower than those of control group, and monoamine neurotransmitters HVA and 5-HIAA content in serum were lower than those of control group while MHPG content was higher than that of control group. Conclusions: Laparoscopic ureterolithotomy can improve the treatment effectiveness and safety for patients with complicated upper ureteral calculi, and it is a more ideal way of lithotomy.