Impact of Hybrid and Complex N-Glycans on Cell Surface Targeting of the Endogenous Chloride Cotransporter Slc12a2

The Na+K+2Cl− cotransporter-1 (Slc12a2, NKCC1) is widely distributed and involved in cell volume/ion regulation. Functional NKCC1 locates in the plasma membrane of all cells studied, particularly in the basolateral membrane of most polarized cells. Although the mechanisms involved in plasma membrane...

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Bibliographic Details
Main Authors: Richa Singh, Mohammed Mashari Almutairi, Romario Pacheco-Andrade, Mohamed Y. Mahmoud Almiahuob, Mauricio Di Fulvio
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:International Journal of Cell Biology
Online Access:http://dx.doi.org/10.1155/2015/505294