A novel imaging method for correlating 2D light microscopic data and 3D volume data based on block-face imaging
Abstract We have developed an imaging method designated as correlative light microscopy and block-face imaging (CoMBI), which contributes to improve the reliability of morphological analyses. This method can collect both the frozen sections and serial block-face images in a single specimen. The froz...
Main Authors: | Yuki Tajika, Tohru Murakami, Keiya Iijima, Hiroki Gotoh, Maiko Takahashi-Ikezawa, Hitoshi Ueno, Yuhei Yoshimoto, Hiroshi Yorifuji |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2017-06-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-017-03900-9 |
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