Characterization of protective immune responses induced by pneumococcal surface protein A in fusion with pneumolysin derivatives.

Pneumococcal surface protein A (PspA) and Pneumolysin derivatives (Pds) are important vaccine candidates, which can confer protection in different models of pneumococcal infection. Furthermore, the combination of these two proteins was able to increase protection against pneumococcal sepsis in mice....

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Bibliographic Details
Main Authors: Cibelly Goulart, Thais Raquel da Silva, Dunia Rodriguez, Walter Rodrigo Politano, Luciana C C Leite, Michelle Darrieux
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3606166?pdf=render