Functional impairment of Tax-specific but not cytomegalovirus-specific CD8<sup>+ </sup>T lymphocytes in a minor population of asymptomatic human T-cell leukemia virus type 1-carriers

<p>Abstract</p> <p>Background</p> <p>Human T-cell leukemia virus type 1 (HTLV-1) causes adult T-cell leukemia (ATL) and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) in a small percentage of infected individuals. ATL is often associated with genera...

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Main Authors: Takamori Ayako, Hasegawa Atsuhiko, Utsunomiya Atae, Maeda Yasuhiro, Yamano Yoshihisa, Masuda Masato, Shimizu Yukiko, Tamai Yotaro, Sasada Amane, Zeng Na, Choi Ilseung, Uike Naokuni, Okamura Jun, Watanabe Toshiki, Masuda Takao, Kannagi Mari
Format: Article
Language:English
Published: BMC 2011-12-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/8/1/100