Glucose homeostasis changes and pancreatic β-cell proliferation after switching to cyclosporin in tacrolimus-induced diabetes mellitus

Glucose homeostasis changes and pancreatic β-cell proliferation after switching to cyclosporin in tacrolimus-induced diabetes mellitus

Background: Switching to cyclosporin A may result in a reversion of tacrolimus-induced diabetes mellitus. However, mechanisms underlying such a reversion are still unknown. Methods: Obese Zucker rats were used as a model for tacrolimus-induced diabetes mellitus. A cohort of 44 obese Zucker rats rece...

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Bibliographic Details
Main Authors: Ana Elena Rodríguez-Rodríguez, Javier Triñanes, Esteban Porrini, Silvia Velázquez-García, Cecilia Fumero, María Jose Vega-Prieto, María Luisa Díez-Fuentes, Sergio Luis Lima, Eduardo Salido, Armando Torres
Format: Article
Language:English
Published: Elsevier 2015-05-01
Series:Nefrología (English Edition)
Subjects:
Post-transplant diabetes mellitus
Tacrolimus
Cyclosporin A
Online Access:http://www.sciencedirect.com/science/article/pii/S2013251415000255

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http://www.sciencedirect.com/science/article/pii/S2013251415000255

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