Impact of DJ-1 and Helix 8 on the Proteome and Degradome of Neuron-Like Cells

Impact of DJ-1 and Helix 8 on the Proteome and Degradome of Neuron-Like Cells

DJ-1 is an abundant and ubiquitous component of cellular proteomes. DJ-1 supposedly exerts a wide variety of molecular functions, ranging from enzymatic activities as a deglycase, protease, and esterase to chaperone functions. However, a consensus perspective on its molecular function in the cellula...

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Bibliographic Details
Main Authors: Ursula Kern, Klemens Fröhlich, Johanna Bedacht, Nico Schmidt, Martin L. Biniossek, Nicole Gensch, Katja Baerenfaller, Oliver Schilling
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Cells
Subjects:
PARK7
parkinson disease
neurodegenerative disease
protease
glycase
TAILS
Online Access:https://www.mdpi.com/2073-4409/10/2/404

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