Homophilic and Heterophilic Interactions of Type II Cadherins Identify Specificity Groups Underlying Cell-Adhesive Behavior

Homophilic and Heterophilic Interactions of Type II Cadherins Identify Specificity Groups Underlying Cell-Adhesive Behavior

Summary: Type II cadherins are cell-cell adhesion proteins critical for tissue patterning and neuronal targeting but whose molecular binding code remains poorly understood. Here, we delineate binding preferences for type II cadherin cell-adhesive regions, revealing extensive heterophilic interaction...

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Bibliographic Details
Main Authors: Julia Brasch, Phinikoula S. Katsamba, Oliver J. Harrison, Göran Ahlsén, Regina B. Troyanovsky, Indrajyoti Indra, Anna Kaczynska, Benjamin Kaeser, Sergey Troyanovsky, Barry Honig, Lawrence Shapiro
Format: Article
Language:English
Published: Elsevier 2018-05-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718305412

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http://www.sciencedirect.com/science/article/pii/S2211124718305412

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