Endocannabinoids Released in the Ventral Tegmental Area During Copulation to Satiety Modulate Changes in Glutamate Receptors Associated With Synaptic Plasticity Processes

Endocannabinoids Released in the Ventral Tegmental Area During Copulation to Satiety Modulate Changes in Glutamate Receptors Associated With Synaptic Plasticity Processes

Endocannabinoids modulate mesolimbic (MSL) dopamine (DA) neurons firing at the ventral tegmental area (VTA). These neurons are activated by copulation, increasing DA release in nucleus accumbens (NAcc). Copulation to satiety in male rats implies repeated ejaculation within a short period (around 2.5...

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Bibliographic Details
Main Authors: Gabriela Rodríguez-Manzo, Estefanía González-Morales, René Garduño-Gutiérrez
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Synaptic Neuroscience
Subjects:
endocannabinoids
CB1 receptors
AMPA and NMDA glutamate receptors
mesolimbic circuit
ventral tegmental area
synaptic plasticity
Online Access:https://www.frontiersin.org/articles/10.3389/fnsyn.2021.701290/full

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