Recurrence-related Factors of 46 Stage Ⅰ-Ⅱ Endometrial Carcinoma Patients

• Main Authors: ZHANG Zhengyu, LING Jingxian, LI Rong, HAN Ke, ZHU Xianghong, TANG Xiaoqiu, ZHOU Huaijun
• Format: Article
• Language: zho
• Published: Magazine House of Cancer Research on Prevention and Treatment 2019-09-01
• Series: Zhongliu Fangzhi Yanjiu
• Subjects: endometrial carcinoma; recurrence; multivariate analysis
• Online Access: http://html.rhhz.net/ZLFZYJ/html/8578.2019.19.0318.htm

Objective To investigate the risk factors of the recurrence of stage Ⅰ-Ⅱ endometrial carcinoma. Methods We retrospectively analyzed the data of 516 patients with stage Ⅰ-Ⅱ endometrial carcinoma treated in Nanjing Drum Tower Hospital from January 2010 to December 2017. The recurrence rate of the patients was followed up. Results The recurrence rate was 8.91%(46/516). Age, body weight, hypertension, stage of operation and pathology, pathological type, low expression of ER and PR were correlated with the recurrence of stage Ⅰ-Ⅱ endometrial carcinoma (P < 0.05). Diabetes mellitus, vascular metastasis, pathological differentiation, lymph node excision and ascites cytologic examination were not correlated with the recurrence of stage Ⅰ-Ⅱ endometrial carcinoma (P > 0.05). Age, body weight and blood pressure were independent risk factors for the recurrence of stageⅠ-Ⅱendometrial carcinoma (P < 0.05). Conclusion Age, body weight, hypertension, stage of operation and pathology, pathological type, low expression of ER and PR affect the recurrence of stage Ⅰ-Ⅱ endometrial carcinoma. Advanced age, low body weight and hypertension are independent risk factors for the recurrence of stage Ⅰ-Ⅱ endometrial carcinoma. In clinical work, we should follow up closely stage Ⅰ-Ⅱ endometrial carcinoma patients with advanced age, low body weight and hypertension, for early detection and in-time treatment of recurrence lesions.