Bone targeting compounds for radiotherapy and imaging: *Me(III)-DOTA conjugates of bisphosphonic acid, pamidronic acid and zoledronic acid

Bone targeting compounds for radiotherapy and imaging: *Me(III)-DOTA conjugates of bisphosphonic acid, pamidronic acid and zoledronic acid

Abstract Background Bisphosphonates have a high adsorption on calcified tissues and are commonly used in the treatment of bone disorder diseases. Conjugates of bisphosphonates with macrocyclic chelators open new possibilities in bone targeted radionuclide imaging and therapy. Subsequent to positron...

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Bibliographic Details
Main Authors: M. Meckel, R. Bergmann, M. Miederer, F. Roesch
Format: Article
Language:English
Published: SpringerOpen 2016-09-01
Series:EJNMMI Radiopharmacy and Chemistry
Subjects:
Hydroxy bisphosphonates
PET
Theranostics
Bone metastases
68Ga
177Lu
Online Access:http://link.springer.com/article/10.1186/s41181-016-0017-1

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