A simple and low-cost poly (dl-phenylalanine) modified carbon sensor for the improved electrochemical analysis of Riboflavin

• Main Authors: N. Hareesha, J.G. Manjunatha
• Format: Article
• Language: English
• Published: Elsevier 2020-12-01
• Series: Journal of Science: Advanced Materials and Devices
• Subjects: Riboflavin; dl-Phenylalanine; Heterogeneous rate constant; Impedance study; Voltammetry
• Online Access: http://www.sciencedirect.com/science/article/pii/S2468217920300678

The current study reports on the electroanalysis of Riboflavin (RF) on the surface of a poly dl-phenylalanine modified carbon paste sensor (PDLPAMCPS). The developed sensor caused a noticeable electrocatalytic action for the redox activity of RF in a phosphate buffer solution (PBS) of pH 6.5. This analysis was evaluated using differential pulse voltammetry (DPV) and cyclic voltammetry (CV) techniques. The active surface of the functioning sensor exposes well developed anodic peak with prominent electron transfer. PDLPAMCPS shows distinctive and improved DPV and CV peaks for RF with and without the presence of organic dyes and dopamine (DA). The impact of the solution pH, scan rate, accumulation potential and concentration on RF at PDLPAMCPS were studied. A vibrant linear growth was observed between the oxidation peak current and the RF concentration in the range of 6.0 μM–30.0 μM, which provides a lower limit of detection (LOD) of 92 nM with excellent sensitivity. The proposed method and sensor were applied for the assessment of RF in medicine sample as an analytical application with fine recoveries and low LOD.