A novel diagnostic target in the hepatitis C virus genome.

<h4>Background</h4>Detection and quantification of hepatitis C virus (HCV) RNA is integral to diagnostic and therapeutic regimens. All molecular assays target the viral 5'-noncoding region (5'-NCR), and all show genotype-dependent variation of sensitivities and viral load resul...

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Main Authors: Jan Felix Drexler, Bernd Kupfer, Nadine Petersen, Rejane Maria Tommasini Grotto, Silvia Maria Corvino Rodrigues, Klaus Grywna, Marcus Panning, Augustina Annan, Giovanni Faria Silva, Jill Douglas, Evelyn S C Koay, Heidi Smuts, Eduardo M Netto, Peter Simmonds, Maria Inês de Moura Campos Pardini, W Kurt Roth, Christian Drosten
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-02-01
Series:PLoS Medicine
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19209955/?tool=EBI