In Xenopus ependymal cilia drive embryonic CSF circulation and brain development independently of cardiac pulsatile forces

In Xenopus ependymal cilia drive embryonic CSF circulation and brain development independently of cardiac pulsatile forces

Abstract Background Hydrocephalus, the pathological expansion of the cerebrospinal fluid (CSF)-filled cerebral ventricles, is a common, deadly disease. In the adult, cardiac and respiratory forces are the main drivers of CSF flow within the brain ventricular system to remove waste and deliver nutrie...

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Bibliographic Details
Main Authors: A. H. Dur, T. Tang, S. Viviano, A. Sekuri, H. R. Willsey, H. D. Tagare, K. T. Kahle, E. Deniz
Format: Article
Language:English
Published: BMC 2020-12-01
Series:Fluids and Barriers of the CNS
Subjects:
Congenital hydrocephalus
Ependymal cilia
Optical coherence tomography
Xenopus tropicalis
Embryonic CSF circulation
Online Access:https://doi.org/10.1186/s12987-020-00234-z

Internet

https://doi.org/10.1186/s12987-020-00234-z

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