Direct Current Stimulation Disrupts Endothelial Glycocalyx and Tight Junctions of the Blood-Brain Barrier in vitro

Direct Current Stimulation Disrupts Endothelial Glycocalyx and Tight Junctions of the Blood-Brain Barrier in vitro

Transcranial direct current stimulation (tDCS) is a non-invasive physical therapy to treat many psychiatric disorders and to enhance memory and cognition in healthy individuals. Our recent studies showed that tDCS with the proper dosage and duration can transiently enhance the permeability (P) of th...

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Bibliographic Details
Main Authors: Yifan Xia, Yunfei Li, Wasem Khalid, Marom Bikson, Bingmei M. Fu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
solute permeability
trans-endothelial electrical resistance (TEER)
heparan sulfate
ZO-1
inhibition of endothelial nitric oxide synthase (eNOS)
human cerebral microvascular endothelial cells
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.731028/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.731028/full

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