Extracellular Protein Aggregates Colocalization and Neuronal Dystrophy in Comorbid Alzheimer’s and Creutzfeldt–Jakob Disease: A Micromorphological Pilot Study on 20 Brains

Extracellular Protein Aggregates Colocalization and Neuronal Dystrophy in Comorbid Alzheimer’s and Creutzfeldt–Jakob Disease: A Micromorphological Pilot Study on 20 Brains

Alzheimer’s disease (AD) and sporadic Creutzfeldt–Jakob disease (sCJD) are both characterized by extracellular pathologically conformed aggregates of amyloid proteins—amyloid β-protein (Aβ) and prion protein (PrP<sup>Sc</sup>), respectively. To investigate the potential morphological col...

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Bibliographic Details
Main Authors: Nikol Jankovska, Tomas Olejar, Radoslav Matej
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
Creutzfeldt–Jakob disease
Alzheimer’s disease
Aβ
prion protein
tau protein
colocalization
Online Access:https://www.mdpi.com/1422-0067/22/4/2099

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