A novel blood-based assay for treatment monitoring of tuberculosis

A novel blood-based assay for treatment monitoring of tuberculosis

Abstract Objectives A novel 3-gene host transcriptional signature (GBP5, DUSP3 and KLF2) has been validated for tuberculosis (TB) treatment monitoring using laboratory-based RNA sequencing platforms. The signature was recently translated by Cepheid into a prototype cartridge-based test that can be r...

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Bibliographic Details
Main Authors: Alexandra J. Zimmer, Samuel G. Schumacher, Erik Södersten, Anna Mantsoki, Romain Wyss, David H. Persing, Sara Banderby, Linda Strömqvist Meuzelaar, Jacqueline Prieto, Devasena Gnanashanmugam, Purvesh Khatri, Stefano Ongarello, Morten Ruhwald, Claudia M. Denkinger
Format: Article
Language:English
Published: BMC 2021-06-01
Series:BMC Research Notes
Subjects:
Tuberculosis
Host transcriptional signature
Treatment monitoring
Online Access:https://doi.org/10.1186/s13104-021-05663-z

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