Genome-wide analysis reveals coating of the mitochondrial genome by TFAM.

Genome-wide analysis reveals coating of the mitochondrial genome by TFAM.

Mitochondria contain a 16.6 kb circular genome encoding 13 proteins as well as mitochondrial tRNAs and rRNAs. Copies of the genome are organized into nucleoids containing both DNA and proteins, including the machinery required for mtDNA replication and transcription. The transcription factor TFAM is...

Full description

Bibliographic Details
Main Authors:	Yun E Wang, Georgi K Marinov, Barbara J Wold, David C Chan
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2013-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC3753274?pdf=render

Similar Items

Evidence for site-specific occupancy of the mitochondrial genome by nuclear transcription factors.
by: Georgi K Marinov, et al.
Published: (2014-01-01)

TFAM-deficient mouse skin fibroblasts – an ex vivo model of mitochondrial dysfunction
by: Manuel J. Del Rey, et al.
Published: (2021-08-01)

Mitochondrial Transcription Factor A (TFAM) Binds to RNA Containing 4-Way Junctions and Mitochondrial tRNA.
by: Timothy A Brown, et al.
Published: (2015-01-01)

Biophysics of V(D)J Recombination and Genome Packaging: In Singulo Studies on RAG, HMGB1, and TFAM
by: Lovely, Geoffrey A.
Published: (2014)

Integrated Genomics Identifies miR-181/TFAM Pathway as a Critical Driver of Drug Resistance in Melanoma
by: Anna Barbato, et al.
Published: (2021-02-01)

Polymorphisms in the autosomal genes for mitochondrial function TFAM and UCP2 are associated with performance and longevity in dairy cows
by: A.M. Clempson, et al.
Published: (2011-01-01)

SIRT-3 Modulation by Resveratrol Improves Mitochondrial Oxidative Phosphorylation in Diabetic Heart through Deacetylation of TFAM
by: Pankaj K. Bagul, et al.
Published: (2018-11-01)

Genome-Wide Adductomics Analysis Reveals Heterogeneity in the Induction and Loss of Cyclobutane Thymine Dimers across Both the Nuclear and Mitochondrial Genomes
by: Alaa S. Alhegaili, et al.
Published: (2019-10-01)

Studies on the structure, function, and regulation of Mitochondrial Transcription Factor A (TFAM) in a Rat Hepatoma /
by: Dong, Xiaocheng
Published: (2002)

Mitochondrial Genome Analysis Reveals Historical Lineages in Yellowstone Bison.
by: David Forgacs, et al.
Published: (2016-01-01)

Genome-wide transposon mutagenesis of paramyxoviruses reveals constraints on genomic plasticity.
by: Satoshi Ikegame, et al.
Published: (2020-10-01)

Genome-wide analysis on the maize genome reveals weak selection on synonymous mutations
by: Duan Chu, et al.
Published: (2020-04-01)

Genome-wide analysis reveals a complex pattern of genomic imprinting in mice.
by: Jason B Wolf, et al.
Published: (2008-06-01)

Genome-wide array comparative genomic hybridization analysis reveals distinct amplifications in osteosarcoma
by: Ladanyi Marc, et al.
Published: (2004-08-01)

Aging and calorie restriction oppositely affect mitochondrial biogenesis through TFAM binding at both origins of mitochondrial DNA replication in rat liver.
by: Anna Picca, et al.
Published: (2013-01-01)

Functional Genomic Studies of the Structure and Regulation of Eukaryotic Transcriptomes
by: Marinov, Georgi Kolev
Published: (2014)

Population Genomic Analysis Reveals a Highly Conserved Mitochondrial Genome in Fusarium asiaticum
by: Meixin Yang, et al.
Published: (2020-05-01)

Association of Thr12Ser polymorphism in mitochondrial transcription factor A TFAM gene with coronary artery disease
by: T. V. Zheikova, et al.
Published: (2012-12-01)

Testosterone Deficiency Caused by Castration Modulates Mitochondrial Biogenesis Through the AR/PGC1α/TFAM Pathway
by: Can Liu, et al.
Published: (2019-05-01)

Expression of mitochondrial regulators PGC1α and TFAM as putative markers of subtype and chemoresistance in epithelial ovarian carcinoma.
by: Marike Gabrielson, et al.
Published: (2014-01-01)

PDE2 Inhibits PKA-Mediated Phosphorylation of TFAM to Promote Mitochondrial Ca2+-Induced Colorectal Cancer Growth
by: Yilin Zhao, et al.
Published: (2021-06-01)

SPIN reveals genome-wide landscape of nuclear compartmentalization
by: Yuchuan Wang, et al.
Published: (2021-01-01)

Genome-Wide Analysis Reveals Novel Regulators of Growth in Drosophila melanogaster.
by: Sibylle Chantal Vonesch, et al.
Published: (2016-01-01)

Correction: Mitochondrial Genome Sequences Effectively Reveal the Phylogeny of Gibbons.
by: Yi-Chiao Chan, et al.
Published: (2013-01-01)

Mitochondrial genome sequences effectively reveal the phylogeny of Hylobates gibbons.
by: Yi-Chiao Chan, et al.
Published: (2010-01-01)

Comparative mitochondrial genome analysis of Daphnis nerii and other lepidopteran insects reveals conserved mitochondrial genome organization and phylogenetic relationships.
by: Yu Sun, et al.
Published: (2017-01-01)

Genomic diversity dynamics in conserved chicken populations are revealed by genome-wide SNPs
by: Mengmeng Zhang, et al.
Published: (2018-08-01)

Genome-Wide Association Analyses Reveal Genomic Regions Controlling Canopy Wilting in Soybean
by: Clinton J. Steketee, et al.
Published: (2020-04-01)

Genome-wide analysis reveals selection for Chinese Rongchang pigs
by: Lei CHEN, Shilin TIAN, Long JIN, Zongyi GUO, Dan ZHU, Lan JING, Tiandong CHE, Qianzi TANG, Siqing CHEN, Liang ZHANG, Tinghuan ZHANG, Zuohua LIU, Jinyong WANG, Mingzhou LI
Published: (2017-09-01)

Programmable Base Editing of the Sheep Genome Revealed No Genome-Wide Off-Target Mutations
by: Shiwei Zhou, et al.
Published: (2019-03-01)

Overexpression of TFAM or twinkle increases mtDNA copy number and facilitates cardioprotection associated with limited mitochondrial oxidative stress.
by: Masataka Ikeda, et al.
Published: (2015-01-01)

Complete mitochondrial genomes reveal neolithic expansion into Europe.
by: Qiaomei Fu, et al.
Published: (2012-01-01)

Genome-wide diversity in the levant reveals recent structuring by culture.
by: Marc Haber, et al.
Published: (2013-01-01)

Genome complexity reduction for genome-wide single nucleotide polymorphism analysis
by: Jordan, Barbara M. (Barbara Marie), 1975-
Published: (2005)

The mitochondrial genome of soybean reveals complex genome structures and gene evolution at intercellular and phylogenetic levels.
by: Shengxin Chang, et al.
Published: (2013-01-01)

TFAM is a novel mediator of immunogenic cancer cell death
by: Minghua Yang, et al.
Published: (2018-06-01)

Multi-Locus Genome-Wide Association Studies Reveal Fruit Quality Hotspots in Peach Genome
by: Cassia da Silva Linge, et al.
Published: (2021-02-01)

Correction: Mitochondrial Genome Sequences Effectively Reveal the Phylogeny of Hylobates Gibbons
by: Yi-Chiao Chan, et al.
Published: (2013-01-01)

Genome-Wide Association Studies in Indian Buffalo Revealed Genomic Regions for Lactation and Fertility
by: Vikas Vohra, et al.
Published: (2021-09-01)

Genom Mitokondria (MITOCHONDRIAL GENOME)
by: I Nengah Wandiya
Published: (2016-08-01)

Cannot write session to /tmp/vufind_sessions/sess_lln2i06cqv50en1bbtm61ski0l