Selective Induction of Cancer Cell Death by Targeted Granzyme B

The potential utility of immunotoxins for cancer therapy has convincingly been demonstrated in clinical studies. Nevertheless, the high immunogenicity of their bacterial toxin domain represents a critical limitation, and has prompted the evaluation of cell-death inducing proteins of human origin as...

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Bibliographic Details
Main Authors: Robert A. Jabulowsky, Pranav Oberoi, Winfried S. Wels
Format: Article
Language:English
Published: MDPI AG 2013-02-01
Series:Antibodies
Subjects:
Online Access:http://www.mdpi.com/2073-4468/2/1/130