RT-qPCR Assays for Rapid Detection of the N501Y, 69-70del, K417N, and E484K SARS-CoV-2 Mutations: A Screening Strategy to Identify Variants With Clinical Impact

RT-qPCR Assays for Rapid Detection of the N501Y, 69-70del, K417N, and E484K SARS-CoV-2 Mutations: A Screening Strategy to Identify Variants With Clinical Impact

BackgroundSeveral variants of the SARS-CoV-2 have been documented globally during the current COVID-19 pandemic. The N501Y, 69-70del, K417N, and E484K SARS-CoV-2 mutations have been documented among the most relevant due to their potential pathogenic biological effects. This study aimed to design, v...

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Bibliographic Details
Main Authors: Natali Vega-Magaña, Rocío Sánchez-Sánchez, Jorge Hernández-Bello, Alberto Antony Venancio-Landeros, Marcela Peña-Rodríguez, Rosa Alejandra Vega-Zepeda, Byron Galindo-Ornelas, Mauricio Díaz-Sánchez, Mariel García-Chagollán, Gabriela Macedo-Ojeda, Octavio Patricio García-González, José Francisco Muñoz-Valle
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
SARS-CoV-2
E484K
P.2 variant detection
SARS-CoV-2 mutations
SARS-CoV-2 mutation screening
molecular screening
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2021.672562/full

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https://www.frontiersin.org/articles/10.3389/fcimb.2021.672562/full

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