Turnover of BRCA1 involves in radiation-induced apoptosis.

Turnover of BRCA1 involves in radiation-induced apoptosis.

Germ-line mutations of the breast cancer susceptibility gene-1 (BRCA1) increase the susceptibility to tumorigenesis. The function of BRCA1 is to regulate critical cellular processes, including cell cycle progression, genomic integrity, and apoptosis. Studies on the regulation of BRCA1 have focused i...

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Bibliographic Details
Main Authors: Weijun Liu, Wenjun Zong, George Wu, Takeo Fujita, Wenqi Li, Judy Wu, Yong Wan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-12-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3013096?pdf=render

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