Influence of Temperature on Transdermal Penetration Enhancing Mechanism of Borneol: A Multi-Scale Study

Influence of Temperature on Transdermal Penetration Enhancing Mechanism of Borneol: A Multi-Scale Study

The influence of temperature on the transdermal permeation enhancing mechanism of borneol (BO) was investigated using a multi-scale method, containing a coarse-grained molecular dynamic (CG-MD) simulation, an in vitro permeation experiment, and a transmission electron microscope (TEM) study. The res...

Full description

Bibliographic Details
Main Authors:	Qianqian Yin, Ran Wang, Shufang Yang, Zhimin Wu, Shujuan Guo, Xingxing Dai, Yanjiang Qiao, Xinyuan Shi
Format:	Article
Language:	English
Published:	MDPI AG 2017-01-01
Series:	International Journal of Molecular Sciences
Subjects:	multi-scale coarse-grained temperature borneol penetration enhancement
Online Access:	http://www.mdpi.com/1422-0067/18/1/195

Similar Items

A Molecular Interpretation on the Different Penetration Enhancement Effect of Borneol and Menthol towards 5-Fluorouracil
by: Ran Wang, et al.
Published: (2017-12-01)

Effects of Concentrations on the Transdermal Permeation Enhancing Mechanisms of Borneol: A Coarse-Grained Molecular Dynamics Simulation on Mixed-Bilayer Membranes
by: Xingxing Dai, et al.
Published: (2016-08-01)

Design, characterization and comparison of transdermal delivery of colchicine via borneol-chemically-modified and borneol-physically-modified ethosome
by: Yujia Zhang, et al.
Published: (2019-01-01)

Investigation of borneols sold in Taiwan by chiral gas chromatography
by: Tsung-Jung Ho, et al.
Published: (2018-01-01)

Interactions of Borneol with DPPC Phospholipid Membranes: A Molecular Dynamics Simulation Study
by: Qianqian Yin, et al.
Published: (2014-11-01)

Progress in Borneol Intervention for Ischemic Stroke: A Systematic Review
by: Yong Li, et al.
Published: (2021-05-01)

Oxidação do borneol à cânfora com água sanitária - um experimento simples, de baixo custo e limpo Oxidation of borneol to camphor with bleach: a simple, green chemistry and inexpensive experiment
by: Ana Paula Bernardo dos Santos, et al.
Published: (2009-01-01)

Enhanced Anti-Glioma Efficacy by Borneol Combined With CGKRK-Modified Paclitaxel Self-Assembled Redox-Sensitive Nanoparticles
by: Lingyan Lv, et al.
Published: (2020-04-01)

Enhancing both oral bioavailability and brain penetration of puerarin using borneol in combination with preparation technologies
by: Tao Yi, et al.
Published: (2017-01-01)

Comparison of Chemical Profiles, Anti-Inflammatory Activity, and UPLC-Q-TOF/MS-Based Metabolomics in Endotoxic Fever Rats between Synthetic Borneol and Natural Borneol
by: Liang Zou, et al.
Published: (2017-08-01)

Preparation, Characterization and in vivo Study of Borneol-Baicalin-Liposomes for Treatment of Cerebral Ischemia-Reperfusion Injury
by: Zhang Y, et al.
Published: (2020-08-01)

Folate and Borneol Modified Bifunctional Nanoparticles for Enhanced Oral Absorption
by: Yifan Yang, et al.
Published: (2018-09-01)

The Effect of Camphor and Borneol on Rat Thymocyte Viability and Oxidative Stress
by: Denitsa Yancheva, et al.
Published: (2012-08-01)

Additive Neuroprotective Effect of Borneol with Mesenchymal Stem Cells on Ischemic Stroke in Mice
by: Xiao-Guang Zhang, et al.
Published: (2018-01-01)

New type of borneol-based fluorine-free superhydrophobic antibacterial polymeric coating
by: Xin Chen, et al.
Published: (2021-01-01)

Bioavailability and Brain-Targeting of Geniposide in Gardenia-Borneol Co-Compound by Different Administration Routes in Mice
by: Xuejiao Zhao, et al.
Published: (2012-11-01)

Anti-inflammatory and healing action of oral gel containing borneol monoterpene in chemotherapy-induced mucositis in rats ( Rattus norvegicus )
by: Braz José do Nascimento-Júnior, et al.
Published: (2017-07-01)

Enhanced anticancer efficiency of doxorubicin against human glioma by natural borneol through triggering ROS-mediated signal
by: Wen-qiang Cao, et al.
Published: (2019-10-01)

Synergistic Effect of Chemical Penetration Enhancers on Lidocaine Permeability Revealed by Coarse-Grained Molecular Dynamics Simulations
by: Marine E. Bozdaganyan, et al.
Published: (2021-05-01)

Natural borneol is a novel chemosensitizer that enhances temozolomide-induced anticancer efficiency against human glioma by triggering mitochondrial dysfunction and reactive oxide species-mediated oxidative damage
by: Liu WJ, et al.
Published: (2018-09-01)

Mining of candidate genes involved in the biosynthesis of dextrorotatory borneol in Cinnamomum burmannii by transcriptomic analysis on three chemotypes
by: Zerui Yang, et al.
Published: (2020-06-01)

l-Borneol Exerted the Neuroprotective Effect by Promoting Angiogenesis Coupled With Neurogenesis via Ang1-VEGF-BDNF Pathway
by: Rong Ma, et al.
Published: (2021-03-01)

Bornyl Diphosphate Synthase From Cinnamomum burmanni and Its Application for (+)-Borneol Biosynthesis in Yeast
by: Rui Ma, et al.
Published: (2021-02-01)

Brain-targeted intranasal delivery of dopamine with borneol and lactoferrin co-modified nanoparticles for treating Parkinson’s disease
by: Shengnan Tang, et al.
Published: (2019-01-01)

Borneol, a novel agent that improves central nervous system drug delivery by enhancing blood–brain barrier permeability
by: Qun-Lin Zhang, et al.
Published: (2017-01-01)

Enhanced permeability of blood–brain barrier and targeting function of brain via borneol-modified chemically solid lipid nanoparticle
by: Song H, et al.
Published: (2018-03-01)

Síntese e desenvolvimento de um modelo de QSAR para derivados do (-)-borneol contra larvas de Aedes aegypti
by: Martins, Ulisses Nicola
Published: (2017)

Natural Terpenes as Penetration Enhancers for Transdermal Drug Delivery
by: Jun Chen, et al.
Published: (2016-12-01)

Borneol and Α-asarone as adjuvant agents for improving blood–brain barrier permeability of puerarin and tetramethylpyrazine by activating adenosine receptors
by: Jun-Yong Wu, et al.
Published: (2018-01-01)

Optimization of the Preparation Conditions of Borneol-Modified Ginkgolide Liposomes by Response Surface Methodology and Study of Their Blood Brain Barrier Permeability
by: Zhiyang Lv, et al.
Published: (2018-01-01)

Borneol Attenuates Ultrasound-Targeted Microbubble Destruction-Induced Blood–Brain Barrier Opening in Focal Cerebral Ischemia
by: Xiao-guang Zhang, et al.
Published: (2017-12-01)

Transdermal penetration of acyclovir in the presence and absence of terpenes / Mariaan Myburgh
by: Myburgh, Mariaan
Published: (2009)

Transdermal penetration of acyclovir in the presence and absence of terpenes / Mariaan Myburgh
by: Myburgh, Mariaan
Published: (2009)

Status of surfactants as penetration enhancers in transdermal drug delivery
by: Iti Som, et al.
Published: (2012-01-01)

Nose-to-brain delivery of borneol modified tanshinone IIA nanoparticles in prevention of cerebral ischemia/reperfusion injury
by: Luting Wang, et al.
Published: (2021-01-01)

Metabolism and transcriptome profiling provides insight into the genes and transcription factors involved in monoterpene biosynthesis of borneol chemotype of Cinnamomum camphora induced by mechanical damage
by: Zerui Yang, et al.
Published: (2021-07-01)

Determination of borneol and other chemical compounds of essential oil of Dryobalanops aromatica exudate from Malaysia
by: Ho, ASH, et al.
Published: (2016)

Transdermal drug delivery of labetalol hydrochloride: Feasibility and effect of penetration enhancers
by: Saqib Zafar, et al.
Published: (2010-01-01)

Preparation and evaluation of sustained-release solid dispersions co-loading gastrodin with borneol as an oral brain-targeting enhancer
by: Zheng Cai, et al.
Published: (2014-02-01)

Synergic Neuroprotection Between Ligusticum Chuanxiong Hort and Borneol Against Ischemic Stroke by Neurogenesis via Modulating Reactive Astrogliosis and Maintaining the Blood–Brain Barrier
by: Bin Yu, et al.
Published: (2021-06-01)