Ten‐Year Simulation of the Effects of Denosumab on Bone Remodeling in Human Biopsies

Ten‐Year Simulation of the Effects of Denosumab on Bone Remodeling in Human Biopsies

ABSTRACT Postmenopausal osteoporosis is a disease manifesting in degradation of bone mass and microarchitecture, leading to weakening and increased risk of fracture. Clinical trials are an essential tool for evaluating new treatments and may provide further mechanistic understanding of their effects...

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Bibliographic Details
Main Authors:	Duncan C Tourolle, David W Dempster, Charles Ledoux, Daniele Boaretti, Mauricio Aguilera, Najma Saleem, Ralph Müller
Format:	Article
Language:	English
Published:	Wiley 2021-06-01
Series:	JBMR Plus
Subjects:	BONE HISTOMORPHOMETRY BONE REMODELING OSTEOPOROSIS SIMULATION THERAPEUTICS
Online Access:	https://doi.org/10.1002/jbm4.10494

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